Chinese archeology professor Jack (Jackie Chan) teams up with beautiful Indian professor Ashmita and assistant Kyra to locate lost Magadha treasure. In a Tibetan ice cave, they find the remains of the royal army that had vanished together with the treasure, only to be ambushed by Randall (Sonu Sood), the descendent of a rebel army leader. When they free themselves, their next stop is Dubai where a diamond from the ice cave is to be auctioned. After a series of double-crosses and revelations about their past, Jack and his team travel to a mountain temple in India, using the diamond as a key to unlock the real treasure.

Two years later of their first adventure, Tad Jones and Sara Lavrof have separate lives, he as a simple construction worker studying archaeology to graduate, and she as a renowned archaeologist and explorer. After discovering the final clue of the existence of King Midas' necklace, Sara invites Tad to an exposition in Las Vegas, where he hopes that she accepts turning in his girlfriend. Just before to travel, Tad realizes that the mummy of Paititi has been exiled from the Inca city by help him and he appears on his home, forcing Tad to travel Las Vegas with his dog Jeff and the mummy. But all hopes and dreams of Tad breaks when a millionaire named Jack Rackham kidnaps Sara to force her revealing the location of the three parts of Midas' necklace. Forming team with Tiffany (Sara's scholar), Mummy, the dog Jeff and Belzoni (Sara's pet, a grouch and intelligent bird who talks using show-bills), Tad Jones and his friends will travel around the world trying rescue Sara and defeat Rackham ...

Hoping to bring his family closer together and to recreate his childhood vacation for his own kids, an adult Rusty Griswold takes his wife and two sons on a cross-country road trip to Walley World. Needless to say, things don't go quite as planned.

A desperate American couple discovers all is not what it seems when they uncover a high-stakes underground scam while traveling abroad. To expose the truth and get back to the U.S., they must risk their lives to save their daughter.